discharge of blood
HISTORY OF DESCRIPTION OF KAWASAKI’S DISEASE. TOMISAKU KAVASAKI – FAMOUS JAPANESE PEDIATRIC, AUTHOR OF SYSTEMIC VASCULITIS IN CHILDREN
Kawasaki disease is a systemic vasculitis of unknown etiology, acute onset in infancy or early childhood, with a primary lesion of the coronary arteries. Syndrome or Kawasaki disease is more often observed in children under the age of 5 years and is recognized as the leading cause of acquired heart diseases in children – primarily the pathology of the coronary arteries, which in some cases can persist throughout the patient’s life, leading to coronary heart disease and myocardial infarction in children and young age. Currently, the number of adults with coronary artery disease due to childhood Kawasaki disease, who are hospitalized for acute myocardial infarction for coronary artery bypass grafting or interventional procedures, is increasing. Dilation (ectasia) or aneurysm of the coronary arteries develops in 25% of children who have not received adequate therapy. Treatment, begun in the first 10 days of the disease with the use of immunoglobulin for intravenous administration, reduces this risk to 3-5%. In this regard, two problems of this disease are important: Continue reading
Advances in perinatal medicine, which has been rapidly developing in recent decades, have led to a significant increase in the survival rate of premature babies with very low and extremely low birth weight. However, among preterm infants who have survived critical conditions, follow-up observation shows an increase in the proportion of disabling diseases, including delayed postnatal growth and neurological deficit. It is relevant to find unused reserves for the prevention of growth disorders, neuroprotection, neurorehabilitation and immunotherapy of perinatal brain lesions in premature infants. Such reserves include correction of vitamin D deficiency. Continue reading
Bronchitis is an inflammatory disease of the lungs without
the formation of infiltrative changes in their parenchyma. Bronchitis can be both a manifestation of ARVI and its complication due to the addition of secondary bacterial microflora in the background or after suffering ARVI. The incidence of acute bronchitis in Russia averages 75–250 per 1000 children per year, that is, 2 orders of magnitude higher than pneumonia. Most often in children, bronchitis occurs in the age category of 1-3 years.
Viruses are thought to be the root cause of approximately 90% of cases of acute bronchitis. Despite this, in a prospective study aimed at studying the etiology and outcomes of lower respiratory tract infections in adults, viruses were isolated in only about a quarter of patients with this disease. Continue reading