Immunity is passive in nature and is provided by maternal antibodies. At the same time, its own immune system is in a state of suppression. The phagocytosis system is not developed. The newborn shows little resistance to opportunistic, pyogenic, gram-negative flora. A tendency to generalization of microbial-inflammatory processes, to septic conditions is characteristic. The child is very sensitive to viral infections, against which he is not protected by maternal antibodies. Approximately on the 5th day of life, the first cross in the white blood formula takes place and the absolute and relative predominance of lymphocytes is established.
The second critical period is due to the destruction of maternal antibodies. The primary immune response to infection penetrates through the synthesis of class M immunoglobulins and leaves no immunological memory. Continue reading